SCHEMBL6011906

SCHEMBL6011906

C[CH]/C=C(\C)CC/C=C/C

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 3/20 0.33
NR1I2 O75469 1/20 0.33
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
MEN1 O00255 2/20 0.31
CYP3A4 P08684 2/20 0.31
ALOX15 P16050 2/20 0.31
MAPT P10636 2/20 0.30
UGT1A1 P22309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23149431 1.00 ALDH1A1 (0.38) ALDH1A1KMT2ANR1I2LMNAPGR
SCHEMBL6011909 1.00 ALDH1A1 (0.38) ALDH1A1KMT2ANR1I2LMNAPGR
SCHEMBL2524497 0.91 KMT2A (0.48) ALDH1A1KMT2ANR1I2LMNAPGR
SCHEMBL2524499 0.91 KMT2A (0.48) ALDH1A1KMT2ANR1I2LMNAPGR
SCHEMBL9242080 0.80
SCHEMBL9242078 0.80
SCHEMBL11477506 0.80 ALDH1A1 (0.61) ALDH1A1KMT2ANR1I2LMNAPGR
SCHEMBL11477515 0.80 ALDH1A1 (0.61) ALDH1A1KMT2ANR1I2LMNAPGR
SCHEMBL12973547 0.80 ALDH1A1 (0.61) ALDH1A1KMT2ANR1I2LMNAPGR
SCHEMBL1618947 0.77 ALDH1A1 (0.64) ALDH1A1KMT2ANR1I2LMNAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866531-B2 Oil-resistant lens material and ophthalmic devices Twenty Twenty Therapeutrics LLC (US) 2024-01-09 US disclosed
WO-2021067189-A1 OIL-RESISTANT LENS MATERIAL AND ELECTROWETTING OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC (US) 2021-04-08 WO disclosed
US-20210095063-A1 OIL-RESISTANT LENS MATERIAL AND OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC 2021-04-01 US disclosed
EP-1732915-A2 SCHWEINFURTHIN ANALOGUES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2006-12-20 EP disclosed
WO-2005092878-A2 SCHWEINFURTHIN ANALOGUES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-10-06 WO disclosed