Urea

Urea

SCHEMBL6012142

C=C(OC)OC.NC(N)=O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 3/20 0.44
LMNA P02545 4/20 0.43
OR51E2 Q9H255 1/20 0.43
BLM P54132 2/20 0.38
PMP22 Q01453 2/20 0.38
ALOX15 P16050 2/20 0.38
TSHR P16473 6/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
NFKB1 P19838 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CYP1A2 P05177 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
THPO P40225 1/20 0.33
CRBN Q96SW2 1/20 0.33
CA2 P00918 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL20574027 0.97 ALDH1A1 (0.43) ALDH1A1TDP1LMNAOR51E2BLM
SCHEMBL538238 0.80
Oxalic Acid SCHEMBL9568817 0.80 ALDH1A1 (0.41) ALDH1A1TDP1ALOX15TSHRKEAP1
SCHEMBL14339837 0.80
Urea SCHEMBL587436 0.79 TDP1 (0.44) ALDH1A1TDP1LMNAOR51E2BLM
Urea SCHEMBL28424931 0.78 ALDH1A1 (0.52) ALDH1A1TDP1LMNAOR51E2BLM
Urea SCHEMBL759609 0.77
Urea SCHEMBL4967133 0.77
Methyl Carbamate SCHEMBL15688513 0.77
Urea SCHEMBL48876 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10179829-B2 Modified amino resins ALLNEX NETHERLANDS B.V. (NL) 2019-01-15 US disclosed
EP-2828324-B1 MODIFIED AMINO RESINS ALLNEX IP S À R L (LU) 2017-11-01 EP disclosed
US-20170066866-A1 MODIFIED AMINO RESINS ALLNEX NETHERLANDS B.V. (NL) 2017-03-09 US disclosed
US-9534114-B2 Modified amino resins ALLNEX IP S.A.R.L. (LU) 2017-01-03 US disclosed
US-20150080523-A1 MODIFIED AMINO RESINS ALLNEX NETHERLANDS B.V. (NL) 2015-03-19 US disclosed
CN-104395384-A Modified amino resins CYTEC TECH CORP 2015-03-04 CN disclosed
EP-2828324-A1 MODIFIED AMINO RESINS Allnex IP S.à.r.l. (LU) 2015-01-28 EP disclosed
WO-2013142787-A1 MODIFIED AMINO RESINS CYTEC TECHNOLOGY CORP. (US) 2013-09-26 WO disclosed
US-20060148356-A1 Quick-drying pure cotton fabric with two faces having different properties and a method of producing same GUANGDONG ESQUEL TEXTILES CO., LTD. 2006-07-06 US disclosed