SCHEMBL6012230

SCHEMBL6012230

CC(C)(C)[Si](C)(C)Oc1cc([C]Oc2ccc(Cl)cc2)ccc1Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.32
CA1 P00915 4/20 0.32
CA9 Q16790 4/20 0.32
TBXA2R P21731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6012181 0.90
SCHEMBL2995063 0.72 HTT (0.49)
SCHEMBL6013311 0.71 PREP (0.30)
SCHEMBL28950890 0.71 PREP (0.46) CA12CA1CA9
SCHEMBL14992971 0.70 HTR2A (0.36) CA12CA1CA9
SCHEMBL3963273 0.70 MAPT (0.42) CA12CA1CA9
SCHEMBL16414370 0.70 INPPL1 (0.41) CA9
SCHEMBL6012179 0.69 TSHR (0.48) CA1CA9TBXA2R
SCHEMBL2989844 0.69 S1PR4 (0.42) TBXA2R
SCHEMBL28405752 0.68 MEN1 (0.40) CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735621-A2 NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES Giri, Brij P. (US) 2006-12-27 EP disclosed
WO-2006073424-A9 NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES GIRI BRIJ P (US) 2006-08-24 WO disclosed
WO-2006073424-A2 NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES GIRI BRIJ P (US) 2006-07-13 WO disclosed