Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7474058 | 0.92 | KMT2A (0.46) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6012336 | 0.92 | SIGMAR1 (0.57) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6013004 | 0.90 | SIGMAR1 (0.52) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6012341 | 0.89 | SIGMAR1 (0.51) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6012912 | 0.89 | SIGMAR1 (0.51) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL6012435 | 0.85 | SIGMAR1 (0.53) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL1077100 | 0.78 | SIGMAR1 (0.51) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL21538553 | 0.77 | MEN1 (0.50) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL323955 | 0.75 | SIGMAR1 (0.56) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL1556809 | 0.75 | CYP2D6 (0.50) | SIGMAR1TSHRKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119091-B2 | Triazaspiro[5.5]undecane derivatives and pharmaceutical compositions comprising thereof, as an active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-10-10 | — | — | US | disclosed |