Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013263 | 0.88 | GCGR (0.48) | GCGRLMNAADORA3SLC6A4SLC6A3 | |
| SCHEMBL6012775 | 0.84 | GCGR (0.52) | GCGRLMNAADORA3SLC6A4SLC6A3 | |
| SCHEMBL6012859 | 0.83 | GCGR (0.50) | GCGRLMNANPC1CASP3RAB9A | |
| SCHEMBL5098380 | 0.80 | GCGR (0.84) | GCGRLMNASLC6A4SLC6A3NPC1 | |
| SCHEMBL9263291 | 0.77 | GCGR (0.65) | GCGRLMNASLC6A4SLC6A3NPC1 | |
| SCHEMBL6013145 | 0.76 | GCGR (0.43) | GCGRLMNAADORA3SLC6A4SLC6A3 | |
| SCHEMBL6013044 | 0.76 | ACHE (0.48) | GCGRLMNANPC1RAB9A | |
| SCHEMBL6013125 | 0.76 | GRM6 (0.46) | GCGRLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6012756 | 0.76 | GCGR (0.43) | GCGRLMNAADORA3SLC6A4SLC6A3 | |
| SCHEMBL6012892 | 0.74 | GCGR (0.41) | GCGRLMNAADORA3NPC1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684754-A1 | HMG-COA REDUCTASE INHIBITORS AND METHOD | Bristol-Myers Squibb Company (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005051386-A1 | HMG-COA REDUCTASE INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |