Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013361 | 0.90 | GCGR (0.42) | GCGRPTGS2LMNANPC1RAB9A | |
| SCHEMBL5101638 | 0.85 | GCGR (0.58) | GAAPOLBGCGRHTTALDH1A1 | |
| SCHEMBL6012654 | 0.83 | GAA (0.44) | GAAPOLBGCGRHTTALDH1A1 | |
| SCHEMBL6013125 | 0.82 | GRM6 (0.46) | GAAPOLBGCGRHTTALDH1A1 | |
| SCHEMBL6013263 | 0.78 | GCGR (0.48) | GAAPOLBGCGRHTTALDH1A1 | |
| SCHEMBL6013145 | 0.78 | GCGR (0.43) | GAAPOLBGCGRHTTALDH1A1 | |
| SCHEMBL5095166 | 0.77 | GCGR (0.55) | GAAPOLBGCGRHTTALDH1A1 | |
| SCHEMBL6012775 | 0.73 | GCGR (0.52) | GCGRLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5094915 | 0.72 | GCGR (0.59) | GCGRALDH1A1LMNANPC1RAB9A | |
| SCHEMBL6013116 | 0.72 | GCGR (0.58) | GCGRLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1684754-A1 | HMG-COA REDUCTASE INHIBITORS AND METHOD | Bristol-Myers Squibb Company (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005051386-A1 | HMG-COA REDUCTASE INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-09 | — | — | WO | disclosed |