Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013397 | 1.00 | ESR2 (0.50) | ESR2L3MBTL1ALDH1A1MAPTCYP2C9 | |
| SCHEMBL5690573 | 0.89 | L3MBTL1 (0.50) | ESR2L3MBTL1ALDH1A1MAPTCYP2C9 | |
| SCHEMBL17893391 | 0.79 | ESR2 (0.50) | ESR2L3MBTL1ALDH1A1MAPTMEN1 | |
| SCHEMBL17892441 | 0.79 | ESR2 (0.50) | ESR2L3MBTL1ALDH1A1MAPTMEN1 | |
| SCHEMBL26649191 | 0.77 | ESR2 (0.44) | ESR2ALDH1A1MAPTBCHEOPRM1 | |
| SCHEMBL29240499 | 0.77 | ESR2 (0.56) | ESR2L3MBTL1ALDH1A1MAPTBCHE | |
| SCHEMBL15777843 | 0.76 | ESR2 (0.45) | ESR2L3MBTL1ALDH1A1MAPTMEN1 | |
| SCHEMBL15777840 | 0.76 | ESR2 (0.45) | ESR2L3MBTL1ALDH1A1MAPTMEN1 | |
| SCHEMBL15777838 | 0.76 | ESR2 (0.45) | ESR2L3MBTL1ALDH1A1MAPTMEN1 | |
| SCHEMBL15777837 | 0.76 | ESR2 (0.45) | ESR2L3MBTL1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122678-B2 | Cyclic amino acids and derivatives thereof useful as pharmaceutical agents | WARNER-LAMBERT COMPANY (US) | 2006-10-17 | — | — | US | claimed |