Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 9/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.54 |
| ▸ | PI4KA | P42356 | 2/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1798270 | 0.88 | ADORA2A (0.72) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| Methylglyoxal SCHEMBL6013418 | 0.83 | ADORA2A (0.76) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| Methylglyoxal SCHEMBL6013421 | 0.81 | ADORA2A (0.78) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL2561529 | 0.79 | AHCY (0.66) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1020380 | 0.78 | AHCY (1.00) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL27713663 | 0.76 | EGFR (0.64) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL15577353 | 0.76 | AHCY (0.70) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8186426 | 0.76 | AHCY (1.00) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| Methylglyoxal SCHEMBL6013428 | 0.76 | ADORA2A (0.67) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| Acetic Acid SCHEMBL4107415 | 0.75 | ADORA2A (0.82) | AHCYADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060258612-A1 | CFTR channel modulators | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258612-A1 | CFTR channel modulators | CFTR, SCNN1B, SCNN1A | AHCY 2166/4885ADORA2A 606/4885ADORA1 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.