SCHEMBL6013474

SCHEMBL6013474

N#CC1CC2CCC(C1)N2CC(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAP3K12 Q12852 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6988860 1.00 MAP3K12 (0.30) MAP3K12
SCHEMBL6615596 0.93
SCHEMBL6615599 0.93
SCHEMBL6575595 0.74
SCHEMBL14968349 0.74 SCN9A (0.32) MAP3K12
SCHEMBL7809722 0.74 LMNA (0.43) MAP3K12
SCHEMBL7809720 0.74 LMNA (0.43) MAP3K12
SCHEMBL25706023 0.74 SCN9A (0.34) MAP3K12
SCHEMBL17729376 0.74 MAP3K12 (0.34) MAP3K12
Hydrochloric Acid SCHEMBL7808192 0.72 MAP3K12 (0.34) MAP3K12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1678142-A1 HEXYL CARBOXANILIDES AND THEIR USE FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS Bayer CropScience AG (DE) 2006-07-12 EP disclosed
WO-2005042493-A1 HEXYL CARBOXANILIDES AND THEIR USE FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-05-12 WO disclosed
EP-1051417-B1 PROCESS FOR THE PREPARATION OF 8-AZABICYCLO(3.2.1)OCTANE DERIVATIVES SYNGENTA LTD (GB) 2004-11-03 EP disclosed
US-6573275-B1 Insecticidal compositions comprising and to methods of combatting and controlling insect pests therewith. SYNGENTA LIMITED (GB) 2003-06-03 US disclosed
EP-0946553-B1 8-AZABICYCLO 3.2.1]OCTANE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INSECTICIDES SYNGENTA LTD (GB) 2003-01-29 EP disclosed
EP-0828739-B1 BICYCLIC AMINES AS INSECTICIDES SYNGENTA LTD (GB) 2002-09-11 EP disclosed
US-6391883-B1 INSECTICIDES SYNGENTA LIMITED (GB) 2002-05-21 US disclosed
US-6323343-B1 REACING 8-(HALOUOROETHYL)-8-AZABICYCLO(3.2.1)OCTAN-3-ONE WITH ALKALI METAL CYANIDE IN PRESENCE OF ACID AND BASE, 3-CYANO-3-HYDROXY-8-(2,2,2-TRIFLUOROETHYL)-8-AZABICYCLO(3.2.1) OCTANE SYNGENTA LIMITED (GB) 2001-11-27 US disclosed
US-6316624-B1 RING OPENING OF 8-SUBSTITUTED-8-AZABICYCLO(3.2.1)OCTAN-3-ONE IN PRESENCE OF ACID OR ION EXCHANGE RESIN TO OBTAIN 3-FORMYL-8-(SUBSTITUTED)-8-AZABICYCLO(3.2.1)OCTANE; REACTING WITH SOURCE OF HYDROXYLAMINE TO FORM 3-NITRILE DERIVATIVE SYNGENTA LTD. (GB) 2001-11-13 US disclosed
US-6207676-B1 Bicyclic amines ZENECA LIMITED (GB) 2001-03-27 US disclosed
US-6174894-B1 Bicyclic amine derivatives ZENECA LIMITED (GB) 2001-01-16 US disclosed
EP-1051418-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED 8-AZABICYCLO [3.2.1]OCTANES ZENECA LIMITED (GB) 2000-11-15 EP disclosed
US-6093726-A AN INSECTICIDES, ACARICIDES OR NEMATICIDES ZENECA LIMITED (GB) 2000-07-25 US disclosed
WO-1999029691-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED 8-AZABICYCLO[3.2.1]OCTANES ZENECA LIMITED (GB) 1999-06-17 WO disclosed
EP-0828739-A1 BICYCLIC AMINES AS INSECTICIDES ZENECA LIMITED (GB) 1998-03-18 EP disclosed
WO-1996037494-A1 BICYCLIC AMINES AS INSECTICIDES ZENECA LIMITED (GB) 1996-11-28 WO disclosed