SCHEMBL6013597

SCHEMBL6013597

CC1(C)CCCC(C)(C)N1OC(=O)/C=C/C(=O)ON1C(C)(C)CCCC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
CYP2C19 P33261 1/20 0.37
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6013599 1.00 TSHR (0.37) TSHRNFKB1CYP2C19KEAP1NFE2L2
SCHEMBL344993 0.90 TSHR (0.34) TSHRNFKB1CYP2C19
SCHEMBL344992 0.90 TSHR (0.34) TSHRNFKB1CYP2C19
SCHEMBL1047285 0.84 TSHR (0.35) TSHRNFKB1CYP2C19
SCHEMBL5929180 0.81
SCHEMBL9865161 0.78 TSHR (0.44) TSHRNFKB1CYP2C19
SCHEMBL986872 0.78 TSHR (0.41) TSHRNFKB1CYP2C19
Ammonia Solution, Strong SCHEMBL9791511 0.77 TSHR (0.41) TSHRNFKB1CYP2C19
SCHEMBL7743476 0.77 TSHR (0.38) TSHRNFKB1CYP2C19
SCHEMBL11093396 0.77 TSHR (0.38) TSHRNFKB1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3520845-B1 SYRINGE ASSEMBLY, PREFILLED SYRINGE, SEAL CAP FOR BARREL WITH PUNCTURE NEEDLE, AND SYRINGE ASSEMBLY PACKAGE TERUMO CORP (JP) 2024-04-17 EP disclosed
EP-3338839-B1 SYRINGE ASSEMBLY, PRE-FILLED SYRINGE, SEALING CAP FOR OUTER TUBE AND PACKAGE FOR SYRINGE ASSEMBLY TERUMO CORP (JP) 2023-03-15 EP disclosed
EP-2974762-B1 SYRINGE ASSEMBLY, SYRINGE ASSEMBLY PACKAGING, AND PRE-FILLED SYRINGE TERUMO CORP (JP) 2021-12-08 EP disclosed
EP-2974761-B1 SYRINGE ASSEMBLY, SYRINGE ASSEMBLY PACKAGING, SEAL CAP FOR OUTER CYLINDER, AND PRE-FILLED SYRINGE TERUMO CORP (JP) 2020-08-12 EP disclosed
US-10549048-B2 Syringe assembly, syringe assembly package body, seal cap for barrel, and prefilled syringe TERUMO KABUSHIKI KAISHA (JP) 2020-02-04 US disclosed
EP-3520845-A1 SYRINGE ASSEMBLY, PREFILLED SYRINGE, SEAL CAP FOR BARREL WITH PUNCTURE NEEDLE, AND SYRINGE ASSEMBLY PACKAGE Terumo Kabushiki Kaisha (JP) 2019-08-07 EP disclosed
US-20190217019-A1 ASSEMBLY FOR SYRINGE, PREFILLED SYRINGE, SEAL CAP FOR PIERCING NEEDLE-ATTACHED BARREL, AND PACKAGE FOR ASSEMBLY FOR SYRINGE TERUMO KABUSHIKI KAISHA (JP) 2019-07-18 US disclosed
EP-3192549-B1 SYRINGE ASSEMBLY, SYRINGE ASSEMBLY PACKAGING, OUTER CYLINDER SEAL CAP, AND PREFILLED SYRINGE TERUMO CORP (JP) 2019-07-17 EP disclosed
CN-105102045-B Syringe assembly, syringe assembly package body, outer cylinder sealing cover and precharging injection syringe 泰尔茂株式会社 2019-07-12 CN disclosed
US-10279103-B2 Outer cylinder for prefilled syringe and outer cylinder packaging for prefilled syringes TERUMO KABUSHIKI KAISHA (JP) 2019-05-07 US disclosed
CN-104602740-A Assembly for syringe, assembly package for syringe, and pre-filled syringe TERUMO CORP 2015-05-06 CN disclosed
US-7144932-B2 Low-friction, high-dispersion synthetic resin composition containing fine particles of RB ceramic or CRB ceramic and a method for its preparation MINEBEA CO., LTD. (JP) 2006-12-05 US disclosed
US-7140778-B2 Synthetic resin composites and bearings formed therefrom and method MINEBEA CO., LTD. (JP) 2006-11-28 US disclosed
EP-1528081-A2 Synthetic resin composites and bearings formed therefrom and method Minebea Co., Ltd. (JP) 2005-05-04 EP disclosed
US-6733705-B1 Blow molding method and blow molded product IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-05-11 US disclosed
US-20040013333-A1 Synthetic resin composites and bearings formed therefrom and method MINEBEA, CO., LTD. 2004-01-22 US disclosed
US-20030229161-A1 Low-friction, high-dispersion synthetic resin compositon containing fine particles of RB ceramic or CRB ceramic and a method for its preparation MINEBEA, CO., LTD. 2003-12-11 US disclosed
EP-1116571-A1 BLOW MOLDING METHOD AND BLOW MOLDED PRODUCT IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-07-18 EP disclosed
EP-0812882-A1 LONG-FIBERGLASS REINFORCED POLYOLEFIN MOLDINGS IMPROVED IN WEATHERING RESISTANCE AND COMPOSITIONS USEFUL AS THE RAW MATERIAL THEREFOR KAWASAKI STEEL CORPORATION (JP) 1997-12-17 EP disclosed
US-4569736-A HINDERED AMINE,PHENOL, OR PHOSPHOMORUS ESTER RADIATION RESISTANCE ADDITIVE TERUMO KABUSHIKI KAISHA (JP) 1986-02-11 US disclosed