Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3636946 | 0.91 | FFAR3 (0.36) | TSHRNFKB1CYP2C19FFAR3KMT2A | |
| SCHEMBL986872 | 0.82 | TSHR (0.41) | TSHRNFKB1CYP2C19KMT2AGAA | |
| SCHEMBL7743476 | 0.80 | TSHR (0.38) | TSHRNFKB1CYP2C19GAA | |
| SCHEMBL11093396 | 0.80 | TSHR (0.38) | TSHRNFKB1CYP2C19GAA | |
| Ammonia Solution, Strong SCHEMBL9791511 | 0.80 | TSHR (0.41) | TSHRNFKB1CYP2C19KMT2AGAA | |
| SCHEMBL4951719 | 0.79 | TSHR (0.39) | TSHRNFKB1CYP2C19 | |
| SCHEMBL6013599 | 0.78 | TSHR (0.37) | TSHRNFKB1CYP2C19 | |
| SCHEMBL8308600 | 0.78 | TSHR (0.37) | TSHRNFKB1CYP2C19KMT2AGAA | |
| SCHEMBL195275 | 0.78 | TSHR (0.37) | TSHRNFKB1CYP2C19KMT2AGAA | |
| SCHEMBL6013597 | 0.78 | TSHR (0.37) | TSHRNFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983737-A | LIGHT STABILIZERS FOR POLYMERIC SUBSTRATES | CIBA-GEIGY CORPORATION (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0389420-A1 | Ethylenically unsaturated compounds containing 1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidine moieties, and polymers, copolymers and stabilized compositions | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |