SCHEMBL6013603

SCHEMBL6013603

CCOc1ccc(-c2ccccc2-c2ccc(OCC)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.64
LTA4H P09960 1/20 0.59
NPC1 O15118 5/20 0.55
RAB9A P51151 4/20 0.55
SMN1; SMN2 Q16637 4/20 0.55
KDM4E B2RXH2 3/20 0.55
ALDH1A1 P00352 3/20 0.55
TP53 P04637 3/20 0.55
HPGD P15428 2/20 0.55
RELA Q04206 1/20 0.53
LMNA P02545 1/20 0.53
TDP1 Q9NUW8 2/20 0.52
TSHR P16473 1/20 0.52
MAPT P10636 3/20 0.51
GAA P10253 1/20 0.51
MAPK1 P28482 1/20 0.51
FFAR1 O14842 1/20 0.50
FFAR4 Q5NUL3 1/20 0.50
ABL1 P00519 1/20 0.48
ABCB1 P08183 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5698011 0.96 LTA4H (0.61) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL13211652 0.94 NQO1 (0.56) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL13211673 0.92 NQO1 (0.54) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL14539085 0.88 NPC1 (0.61) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL11021395 0.86 NQO1 (0.52) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL5833074 0.86 FFAR1 (0.58) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL14878585 0.86 NQO1 (0.52) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL21901393 0.86 KDM4E (0.66) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL5709623 0.86 NQO1 (0.52) NQO1LTA4HNPC1RAB9ASMN1; SMN2
SCHEMBL396847 0.86 TDP1 (0.53) NQO1LTA4HNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7122284-B2 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-10-17 US disclosed
US-7071285-B2 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2006-07-04 US disclosed
US-7056633-B2 Electrophotographic photoconductor, image forming method and apparatus, and process cartidge using the photocondutor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-06-06 US disclosed
US-20060035161-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2006-02-16 US disclosed
US-6974654-B2 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTOCONDUCTOR, AND LONG-CHAIN ALKYL GROUP CONTAINING BISPHENOL COMPOUND AND POLYMER MADE THEREFROM RICOH COMPANY, LTD. (JP) 2005-12-13 US disclosed
US-6919419-B2 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTRO-PHOTOGRAPHIC PHOTOCONDUCTOR, ELECTRO-PHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY LTD. (JP) 2005-07-19 US disclosed
US-20050003287-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2005-01-06 US disclosed
US-6790571-B2 FORMED FROM N-(4-(2,2-BIS(4-HYDROXYPHENYL)VINYL)PHENYL)-N,N BIS(4-TOLYL)AMINE; IMPROVED DURABILITY; FOR USE IN ORGANIC ELECTROLUMINESCENT DEVICE RICOH COMPANY, LTD. (JP) 2004-09-14 US disclosed
US-20040131960-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2004-07-08 US disclosed
US-20040002574-A1 Aromatic block polycarbonate resin, diphenol compound for preparation of the polycarbonate resin, electro-photographic photoconductor, electro-photographic image forming apparatus and process, and process cartridge RICOH COMPANY, LTD. (JP) 2004-01-01 US disclosed
US-20030198881-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2003-10-23 US disclosed
US-6576386-B1 AROMATIC BLOCK POLYCARBONATE RESIN, DIPHENOL COMPOUND FOR PREPARATION OF THE POLYCARBONATE RESIN, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2003-06-10 US disclosed
US-6548216-B2 Forming electrostatic latent images RICOH COMPANY, LTD. (JP) 2003-04-15 US disclosed
US-20020098430-A1 Aromatic polycarbonate resin, electrophotographic photoconductor, process cartridge, and electrophotographic image forming method and apparatus RICOH COMPANY, LTD. (JP) 2002-07-25 US disclosed
US-20020025483-A1 Electrophotographic photoconductor, image forming method and apparatus, and process cartridge using the photoconductor, and long-chain alkyl group containing bisphenol compound and polymer made therefrom RICOH COMPANY, LTD. (JP) 2002-02-28 US disclosed
US-6303736-B1 FROM AN OXYPHENYLENE DIOL AND A 1,1-BIS(HYDROXYPHENYL-2-ARYLETHYLENE COMPOUND RICOH COMPANY, LTD. (JP) 2001-10-16 US disclosed
US-6187494-B1 AROMATIC POLYCARBONATE INCLUDING POLYPHENYLENE ETHER PORTIONS; WEAR RESISTANCE RICOH COMPANY, LTD. (JP) 2001-02-13 US disclosed
US-6187492-B1 ELECTROCONDUCTIVE SUPPORT COATED WITH A PHOTOCONDUCTIVE CHARGE TRANSPORT LAYER OF SOLUTION POLYMERIZED COPOLYCARBONATE HAVING TRIARYLAMINE DIPHENOL UNITS AND DIHYDROXY SUBSTITUTED ARYL BENZOATE UNITS; PHOTOSENSITIVITY RICOH COMPANY, LTD. (JP) 2001-02-13 US disclosed