Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151033 | 0.95 | BCHE (0.58) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL31022637 | 0.88 | BCHE (0.69) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL29477373 | 0.88 | BCHE (0.69) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL6726368 | 0.88 | BCHE (0.69) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL6726363 | 0.88 | BCHE (0.69) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL10005478 | 0.84 | TAS2R31 (0.51) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL5857357 | 0.83 | ALDH1A1 (0.76) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL28381344 | 0.83 | BCHE (0.57) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL23813679 | 0.80 | BCHE (0.64) | CYP3A4ALDH1A1HPGDMAPK1HSD17B10 | |
| SCHEMBL11640358 | 0.80 | CYP3A4 (0.59) | CYP3A4ALDH1A1MAPK1CYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105675-A | REDUCING ACYLATED FLAVANONE WITH ALKALI BOROHYDRIDE TO REMOVE OXYGEN FUNCTION AT 4-POSITION; OXIDIZING WITH HALOGENATED BENZOQUINONE TO FORM SALT | THE COCA-COLA COMPANY (US) | 1978-08-08 | — | — | US | claimed |
| US-20060229358-A1 | Pharmaceutical composition containing flavonoids | TAIPEI MEDICAL UNIVERSITY (TW) | 2006-10-12 | — | — | US | disclosed |
| US-4105675-A | REDUCING ACYLATED FLAVANONE WITH ALKALI BOROHYDRIDE TO REMOVE OXYGEN FUNCTION AT 4-POSITION; OXIDIZING WITH HALOGENATED BENZOQUINONE TO FORM SALT | THE COCA-COLA COMPANY (US) | 1978-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229358-A1 | Pharmaceutical composition containing flavonoids | PDE4B, PDE4A, PDE3B | CYP3A4 12/4885ALDH1A1 1668/4885HPGD 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.