Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013884 | 1.00 | PPID (0.40) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL4860453 | 1.00 | PPID (0.40) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL4853309 | 0.90 | MEN1 (0.39) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL14066123 | 0.82 | ALDH1A1 (0.37) | KMT2AKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL28491402 | 0.80 | PPID (0.46) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL4859643 | 0.77 | PPID (0.45) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL14066122 | 0.77 | PPID (0.45) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL4863045 | 0.74 | TSHR (0.53) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL14066124 | 0.74 | TSHR (0.53) | PPIDNPC1KMT2AKDM4EMEN1 | |
| SCHEMBL14066126 | 0.74 | ALDH1A1 (0.36) | KMT2AKDM4EALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666047-A1 | Pharmaceutical compositions comprising nitric oxide-releasing pyrrolidones | The Government of the United States of America As represented by the Secretary of the Department Of Health and Human Services (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-0793500-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NITRIC OXIDE-RELEASING POLYSACCHARIDES | US GOV HEALTH & HUMAN SERV (US) | 2006-05-03 | — | — | EP | disclosed |
| US-6379660-B1 | BIOPOLYMERS; ADMINISTERING THERAPY DOSAGE; ANTITUMOR AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2002-04-30 | — | — | US | disclosed |
| US-6200558-B1 | PEPTIDE, POLYPEPTIDE, PROTEIN, OLIGONUCLEOTIDE OR NUCLEIC ACID, TO WHICH IS BOUND A NITRIC OXIDE-RELEASING N2O2-FUNCTIONAL GROUP | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2001-03-13 | — | — | US | disclosed |
| EP-0804177-A1 | USE OF NITRIC OXIDE-RELEASING AGENTS FOR REDUCING METASTASIS RISK | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) | 1997-11-05 | — | — | EP | disclosed |
| EP-0793500-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NITRIC OXIDE-RELEASING BIOPOLYMERS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996015781-A1 | USE OF NITRIC OXIDE-RELEASING AGENTS FOR REDUCING METASTASIS RISK | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-05-30 | — | — | WO | disclosed |
| WO-1996015797-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NITRIC OXIDE-RELEASING BIOPOLYMERS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-05-30 | — | — | WO | disclosed |