SCHEMBL6014105

SCHEMBL6014105

CC1(C)CC(C(=O)c2ccccc2)C(=O)C(C)(C)N1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
EZH2 Q15910 3/20 0.46
MCL1 Q07820 1/20 0.41
POLB P06746 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
ALOX15 P16050 2/20 0.38
KDM4E B2RXH2 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MAPT P10636 1/20 0.38
HBB P68871 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40016 0.77 GAA (0.59) GAAEZH2POLBHTTKMT2A
SCHEMBL9983428 0.74 MCL1 (0.40) GAAMCL1HTTSMN1; SMN2KMT2A
SCHEMBL10591710 0.72 TP53 (0.31) GAA
SCHEMBL10811765 0.70 GAA (0.42) GAAEZH2POLBCYP3A4CYP2D6
SCHEMBL14431671 0.70 GAA (0.55) GAAEZH2POLBCYP3A4CYP2D6
Benzoic Acid SCHEMBL9813692 0.69 GAA (0.58) GAAEZH2POLBHTTKMT2A
Benzoic Acid SCHEMBL28378807 0.69 GAA (0.58) GAAEZH2POLBHTTKMT2A
SCHEMBL15957188 0.69 GAA (0.47) GAAEZH2POLBCYP3A4CYP2D6
SCHEMBL2908330 0.67 EZH2 (0.89) EZH2POLBKMT2AMEN1L3MBTL1
SCHEMBL97715 0.67 GAA (1.00) GAAEZH2POLBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4267658-A1 CONDENSATION CURABLE COMPOSITION COMPRISING SILOXANE-IMIDE CROSSLINKER Momentive Performance Materials Inc. (US) 2023-11-01 EP disclosed
WO-2022140004-A1 CONDENSATION CURABLE COMPOSITION COMPRISING SILOXANE-IMIDE CROSSLINKER MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-06-30 WO disclosed
US-7018755-B2 Electrophotographic photoconductor, electrophotography method using the same, electrophotographic apparatus, electrographic apparatus process cartridge and electrophotographic photoconductor outermost surface layer coating solution RICOH COMPANY, LTD. (JP) 2006-03-28 US disclosed
US-20040126687-A1 Electrophotographic photoconductor, electrophotography method using the same, electrophotographic apparatus, electrophotographic apparatus process cartridge and electrophotographic photoconductor outermost surface layer coating solution RICOH COMPANY, LTD. (JP) 2004-07-01 US disclosed
EP-0389421-A1 Poly(1-hydrocarbyloxy-2,2,6,6-tetraalkylpiperidine) light stabilizers CIBA-GEIGY AG (CH) 1990-09-26 EP disclosed