SCHEMBL6014116

SCHEMBL6014116

Cn1c(C=O)ccc1C=O

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.50
TRIM33 Q9UPN9 1/20 0.50
ATM Q13315 2/20 0.44
ALDH1A1 P00352 8/20 0.41
GAA P10253 1/20 0.39
CYP1A2 P05177 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KMT2A Q03164 3/20 0.34
CYP2A6 P11509 2/20 0.33
LMNA P02545 2/20 0.32
POLB P06746 1/20 0.32
IMPDH2 P12268 1/20 0.32
MEN1 O00255 2/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GFER P55789 1/20 0.31
HKDC1 Q2TB90 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6237426 0.84
SCHEMBL8655214 0.82
SCHEMBL12482338 0.77 TRIM24 (0.38) TRIM24TRIM33ATMALDH1A1GAA
SCHEMBL6736550 0.75 KMT2A (0.43) TRIM24TRIM33ATMALDH1A1GAA
SCHEMBL17821042 0.75 TRIM24 (0.50) TRIM24TRIM33ATMALDH1A1GAA
SCHEMBL5187727 0.72 LMNA (0.34) TRIM24TRIM33ATMALDH1A1GAA
SCHEMBL21686018 0.71 CA12 (0.50) ALDH1A1LMNA
SCHEMBL22342652 0.70 HIF1A (0.46) ALDH1A1KMT2ALMNAMEN1THRB
SCHEMBL16434601 0.69 TRIM24 (0.39) TRIM24TRIM33ATMALDH1A1KMT2A
SCHEMBL260478 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111635301-B Novel photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2023-03-24 CN claimed
CN-111635301-A Novel photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-08 CN claimed
CN-111620845-A Long-wavelength morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-04 CN claimed
CN-111574425-A Novel benzoyl formic acid methyl ester photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-25 CN claimed
CN-111574352-A Long-wavelength carbonyl alcohol photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-25 CN claimed
CN-111635301-B Novel photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2023-03-24 CN disclosed
CN-111635301-A Novel photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-08 CN disclosed
CN-111620845-A Long-wavelength morpholinyl acetophenone photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-09-04 CN disclosed
CN-111574352-A Long-wavelength carbonyl alcohol photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-25 CN disclosed
CN-111574425-A Novel benzoyl formic acid methyl ester photoinitiator and preparation method thereof 北京化工大学常州先进材料研究院 2020-08-25 CN disclosed
EP-1685836-A2 Antifungal activity of dicationic molecules UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2006-08-02 EP disclosed
EP-0973750-B1 SUBSTITUTED BENZIMIDAZOLES AND THEIR USE FOR TREATING RETROVIRAL INFECTION UNIV NORTH CAROLINA (US) 2004-04-21 EP disclosed
US-5667975-A Method of fluorescent detection of nucleic acids and cytoskeleton elements using bis-dicationic aryl furans THE UNIVERSITY OF NORTH CAROLINA 1997-09-16 US disclosed
US-5643935-A CRYPTOCOCCUS INFECTIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1997-07-01 US disclosed
US-5639755-A THERAPY FOR CRYPTOCOCCUS AND CANDIDA INFECTIONS UNIVERSITY OF NORTH CAROLINA (US) 1997-06-17 US disclosed
WO-1996040997-A1 METHOD OF FLUORESCENT DETECTION OF NUCLEIC ACIDS AND CYTOSKELETON ELEMENTS USING BIS-DICATIONIC ARYL FURANS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-12-19 WO disclosed
WO-1996040145-A1 METHODS OF COMBATTING INFECTIOUS DISEASES USING DICATIONIC BIS-BENZIMIDAZOLES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 1996-12-19 WO disclosed
EP-0041675-B1 4-HALOGEN-5-(TRICHLOROMETHYL-PHENYL)-OXAZOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND RADIATION-SENSITIVE COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1985-12-11 EP disclosed
US-4371607-A 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-01 US disclosed
EP-0041675-A2 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed