Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25360340 | 0.87 | SIGMAR1 (0.54) | SIGMAR1ADRA2A | |
| SCHEMBL6927377 | 0.86 | CCR3 (0.48) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL10819385 | 0.83 | AVPR1A (0.47) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL16836026 | 0.83 | AVPR1A (0.52) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL6926797 | 0.82 | SIGMAR1 (0.57) | SIGMAR1ADRA2AOPRM1OPRD1OPRK1 | |
| SCHEMBL4979408 | 0.78 | AVPR1A (0.53) | SIGMAR1 | |
| SCHEMBL25628434 | 0.77 | AVPR1A (0.47) | SIGMAR1HTR2A | |
| SCHEMBL20629522 | 0.76 | AVPR1A (0.49) | SIGMAR1 | |
| SCHEMBL12013906 | 0.76 | SIGMAR1 (0.65) | SIGMAR1OPRM1 | |
| SCHEMBL11735378 | 0.74 | SIGMAR1 (0.53) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1726590-A1 | CYCLOALKANOPYRIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-29 | — | — | EP | disclosed |