SCHEMBL6015064

SCHEMBL6015064

COC(=O)[C@H](Cc1ccc(-n2c(=O)c3cc(CO)ccc3n(C)c2=O)cc1)NC(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.69

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 20/20 0.69
ITGB7 P26010 20/20 0.69
ITGB1 P05556 18/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13819338 0.93 ITGA4 (0.69) ITGA4ITGB7ITGB1
SCHEMBL13819339 0.93 ITGA4 (0.66) ITGA4ITGB7ITGB1
SCHEMBL17117095 0.92 ITGA4 (0.67) ITGA4ITGB7ITGB1
SCHEMBL4812920 0.91 ITGA4 (0.81) ITGA4ITGB7ITGB1
SCHEMBL181265 0.91 ITGA4 (0.81) ITGA4ITGB7ITGB1
SCHEMBL10329628 0.91 ITGA4 (0.66) ITGA4ITGB7ITGB1
SCHEMBL16489169 0.91 ITGA4 (0.65) ITGA4ITGB7ITGB1
SCHEMBL10329614 0.91 ITGA4 (0.65) ITGA4ITGB7ITGB1
SCHEMBL12955399 0.90 ITGA4 (0.85) ITGA4ITGB7ITGB1
SCHEMBL10329624 0.90 ITGA4 (0.85) ITGA4ITGB7ITGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2803667-A1 Phenylalanine derivatives AJINOMOTO CO., INC. (JP) 2014-11-19 EP disclosed
EP-2615087-A2 Phenylalanine derivatives AJINOMOTO CO., INC. (JP) 2013-07-17 EP disclosed
EP-1700850-A1 NOVEL PHENYLALANINE DERIVATIVE Ajinomoto Co., Inc. (JP) 2006-09-13 EP disclosed