Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015137 | 0.92 | KMT2A (0.46) | CHRM1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL3451660 | 0.86 | CHRM2 (0.41) | CHRM1ALDH1A1MMP1MMP3CYP3A4 | |
| SCHEMBL6014990 | 0.80 | NPC1 (0.39) | MEN1KMT2AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3448775 | 0.79 | FPR2 (0.50) | CHRM1ALDH1A1MMP1MMP3CYP3A4 | |
| SCHEMBL3450523 | 0.79 | FPR2 (0.50) | CHRM1ALDH1A1MMP1MMP3CYP3A4 | |
| SCHEMBL6015041 | 0.78 | CCR1 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL3448753 | 0.78 | — | — | |
| SCHEMBL3449382 | 0.77 | — | — | |
| SCHEMBL3450745 | 0.77 | CCR1 (0.37) | MEN1KMT2A | |
| SCHEMBL6015058 | 0.77 | CCR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |