Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452017 | 0.87 | L3MBTL3 (0.38) | L3MBTL3L3MBTL1F10CCR1SIGMAR1 | |
| SCHEMBL16602550 | 0.77 | CCR1 (0.41) | CCR1ALDH1A1 | |
| SCHEMBL13123133 | 0.77 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1F10CCR1F2 | |
| SCHEMBL3448743 | 0.77 | CCR1 (0.48) | L3MBTL3L3MBTL1F10CCR1F2 | |
| SCHEMBL6015018 | 0.76 | CCR1 (0.41) | CCR1TP53CHRM3 | |
| SCHEMBL3452016 | 0.75 | L3MBTL3 (0.43) | L3MBTL3L3MBTL1F10ALDH1A1CHRM1 | |
| SCHEMBL6014992 | 0.75 | CCR1 (0.42) | CCR1CYP3A4CYP2C19TP53 | |
| SCHEMBL14541506 | 0.75 | CCR3 (0.40) | L3MBTL3L3MBTL1F10CYP3A4CYP2C19 | |
| SCHEMBL4684724 | 0.75 | KMT2A (0.48) | L3MBTL3L3MBTL1CYP3A4CYP2C19 | |
| SCHEMBL3455074 | 0.74 | F10 (0.40) | F10CCR1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |