⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3060811 | 0.67 | — | — | |
| SCHEMBL10215 | 0.59 | — | — | |
| SCHEMBL22062 | 0.59 | — | — | |
| SCHEMBL769166 | 0.59 | — | — | |
| SCHEMBL769165 | 0.59 | — | — | |
| SCHEMBL3749106 | 0.56 | — | — | |
| SCHEMBL4275318 | 0.56 | — | — | |
| SCHEMBL2305995 | 0.56 | — | — | |
| SCHEMBL15226509 | 0.56 | — | — | |
| SCHEMBL268403 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10421722-B2 | Sulfur-containing compounds targeting vesicular acetylcholine transporter | WASHINGTON UNIVERSITY (US) | 2019-09-24 | — | — | US | claimed |
| US-20170355675-A1 | SULFUR-CONTAINING COMPOUNDS TARGETING VESICULAR ACETYLCHOLINE TRANSPORTER | WASHINGTON UNIVERSITY (US) | 2017-12-14 | — | — | US | claimed |
| CN-104603134-A | Amido-benzyl sulfone and sulfoxide derivatives | GENENTECH INC | 2015-05-06 | — | — | CN | claimed |
| US-8497260-B2 | 2-arylbenzothiophene derivatives or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition for the diagnosis or treatment of degenerative brain disease containing the same as active ingredient | Industry-University Cooperation Foundation Sogang University (KR) | 2013-07-30 | — | — | US | claimed |
| US-20100261727-A1 | 2-ARYLBENZOTHIOPHENE DERIVATIVES OR PHARCEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD THEREOF, AND PHARCEUTICAL COMPOSITION FOR THE DIAGNOSIS OR TREATMENT OF DEGENERATIVE BRAIN DISEASE CONTAINING THE SAME AS ACTIVE INGREDIENT | Industry-University Cooperation Foundation Sogang University | 2010-10-14 | — | — | US | claimed |
| WO-2024053650-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST DIACYLGLYCEROL KINASE α AND/OR ζ, AND PHARMACEUTICAL USE THEREOF | 小野薬品工業株式会社 | 2024-03-14 | — | — | WO | disclosed |
| WO-2023139085-A1 | NEW BENZIMIDAZOLE PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-07-27 | — | — | WO | disclosed |
| US-20230219979-A1 | PYRAZOLO[1,5-a]PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | SHENZHEN ZHONGGE BIOLOGICAL TECHNOLOGY CO., LTD. (CN) | 2023-07-13 | — | — | US | disclosed |
| WO-2020022360-A1 | PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | 三井化学アグロ株式会社 | 2020-01-30 | — | — | WO | disclosed |
| US-10439252-B2 | Electrolyte solution for electrochemical device, and electrochemical device | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-08 | — | — | US | disclosed |
| US-10421722-B2 | Sulfur-containing compounds targeting vesicular acetylcholine transporter | WASHINGTON UNIVERSITY (US) | 2019-09-24 | — | — | US | disclosed |
| CN-104969406-B | Electrolyte solution for electrochemical device and electrochemical device | 富士胶片和光纯药株式会社 | 2018-11-02 | — | — | CN | disclosed |
| US-20030114458-A1 | Antibacterial agents | WARNER-LAMBERT COMPANY | 2003-06-19 | — | — | US | disclosed |
| WO-2002096908-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2002-12-05 | — | — | WO | disclosed |
| EP-0898570-A1 | HERBICIDAL HETEROCYCLICALLY SUBSTITUTED BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997038996-A1 | HERBICIDAL HETEROCYCLICALLY SUBSTITUTED BENZOYLISOTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | disclosed |
| US-5407932-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-04-18 | — | — | US | disclosed |
| EP-0393400-B1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KK (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5245037-A | Synthetic bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0393400-A1 | Novel quinolone derivatives, preparation processes thereof, and antibacterial agents containing the same | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-24 | — | — | EP | disclosed |