Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934755 | 1.00 | NPC1 (0.32) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL14554125 | 0.89 | LPL (0.32) | SLC6A2SLC6A4HTR2CHTR2ASPHK1 | |
| SCHEMBL17945981 | 0.89 | RARB (0.31) | HSD17B10 | |
| SCHEMBL16675102 | 0.85 | SPHK2 (0.30) | SPHK1 | |
| SCHEMBL18472742 | 0.82 | — | — | |
| SCHEMBL16276517 | 0.81 | LPL (0.34) | SPHK1GPR3 | |
| SCHEMBL20279901 | 0.80 | CNR2 (0.31) | — | |
| SCHEMBL15132544 | 0.79 | ESR1 (0.42) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL2825081 | 0.79 | ESR1 (0.42) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL29971139 | 0.79 | ESR1 (0.42) | NPC1GAANFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160218291-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2016-07-28 | — | — | US | disclosed |
| WO-2015044656-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2015-04-02 | — | — | WO | disclosed |
| US-20140217376-A1 | ORGANIC LIGHT EMISSIVE MATERIAL AND DEVICE | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2014-08-07 | — | — | US | disclosed |
| WO-2012052713-A1 | ORGANIC LIGHT-EMITTING DEVICE AND METHOD | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2012-04-26 | — | — | WO | disclosed |