Ether

Ether

SCHEMBL6015485

CC(C)(C)c1ccc(O)c(O)c1.CCOCC

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.73
HPGD P15428 1/20 0.73
ALOX15 P16050 1/20 0.73
HSD17B10 Q99714 1/20 0.73
TDP1 Q9NUW8 1/20 0.73
ESR1 P03372 6/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
RECQL P46063 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP2D6 P10635 3/20 0.47
SIRT1 Q96EB6 1/20 0.47
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
RORC P51449 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
AR P10275 1/20 0.41
ESR2 Q92731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28326769 0.86 ALDH1A1 (0.83) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL29358687 0.85 ALDH1A1 (1.00) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL50705 0.85 ALDH1A1 (1.00) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL12078076 0.83 ALDH1A1 (0.95) ALDH1A1HPGDALOX15HSD17B10TDP1
Methyl Alcohol SCHEMBL28496901 0.83 ALDH1A1 (0.95) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL28661434 0.83 ALDH1A1 (0.95) ALDH1A1HPGDALOX15HSD17B10TDP1
SCHEMBL28492326 0.79 ALDH1A1 (0.86) ALDH1A1HPGDALOX15HSD17B10TDP1
Hydroquinone SCHEMBL10608189 0.79 ALDH1A1 (0.86) ALDH1A1HPGDALOX15HSD17B10TDP1
Bicarbonate SCHEMBL8910747 0.78 ALDH1A1 (0.83) ALDH1A1HPGDALOX15HSD17B10TDP1
Ammonia Solution, Strong SCHEMBL11210265 0.77 ALDH1A1 (0.73) ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006074401-A1 ALKYLATION OF HYDROXYARENES WITH OLEFINS, ALCOHOLS AND ETHERS IN IONIC LIQUIDS SI GROUP, INC. (US) 2006-07-13 WO disclosed