Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21098369 | 0.80 | SMN1; SMN2 (0.89) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL10822114 | 0.79 | NAMPT (0.71) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL6015841 | 0.78 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL13373319 | 0.78 | NPC1 (0.61) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL6015856 | 0.77 | RAD52 (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16869435 | 0.76 | CYP19A1 (0.70) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL4484066 | 0.76 | SMN1; SMN2 (0.80) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL10853932 | 0.76 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL95881 | 0.75 | SMN1; SMN2 (0.78) | MEN1KMT2ASMN1; SMN2NPC1POLB | |
| SCHEMBL6571604 | 0.75 | SMN1; SMN2 (0.84) | MEN1KMT2ASMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |