Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30676344 | 0.82 | HTR3A (0.39) | HTR3AALDH1A1KDM4E | |
| SCHEMBL29122792 | 0.82 | HTR3A (0.39) | HTR3AALDH1A1KDM4E | |
| SCHEMBL1786483 | 0.81 | KDM4E (0.52) | ALDH1A1IMPDH2KDM4ESMN1; SMN2HTT | |
| SCHEMBL22774246 | 0.79 | KDM4E (0.42) | HTR3AALDH1A1IMPDH2KDM4EOPRM1 | |
| SCHEMBL29577881 | 0.79 | KDM4E (0.42) | HTR3AALDH1A1IMPDH2KDM4EOPRM1 | |
| SCHEMBL17176610 | 0.76 | HTR3A (0.64) | HTR3AKDM4ENPY5RIL1BP2RX7 | |
| SCHEMBL17176635 | 0.76 | HTR3A (0.64) | HTR3AKDM4ENPY5RIL1BP2RX7 | |
| SCHEMBL17176483 | 0.76 | HTR3A (0.64) | HTR3AKDM4ENPY5RIL1BP2RX7 | |
| SCHEMBL17170652 | 0.73 | HTR3A (0.64) | HTR3AALDH1A1KDM4EIL1BP2RX7 | |
| SCHEMBL19068183 | 0.73 | HTR3A (0.61) | HTR3AKDM4ENPY5RIL1BP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |