Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | LTK | P29376 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.44 |
| ▸ | CDK7 | P50613 | 2/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.44 |
| ▸ | MST1R | Q04912 | 2/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016042 | 1.00 | KDR (0.51) | KDRNTRK1RAB9ANPC1HTT | |
| SCHEMBL6015661 | 0.86 | MIF (0.50) | KDRNTRK1RAB9ANPC1PRKD3 | |
| SCHEMBL6015663 | 0.86 | MIF (0.50) | KDRNTRK1RAB9ANPC1PRKD3 | |
| SCHEMBL6015983 | 0.86 | KDR (0.59) | KDRNTRK1RAB9ANPC1HTT | |
| SCHEMBL6015991 | 0.86 | KDR (0.59) | KDRNTRK1RAB9ANPC1HTT | |
| SCHEMBL6016071 | 0.79 | KDR (0.55) | KDRNTRK1RAB9ANPC1HTT | |
| SCHEMBL6016074 | 0.79 | KDR (0.55) | KDRNTRK1RAB9ANPC1HTT | |
| SCHEMBL5201381 | 0.78 | NTRK1 (0.73) | KDRNTRK1NPC1PRKD3ABL1 | |
| SCHEMBL6015653 | 0.75 | KDR (0.73) | KDRNTRK1RAB9APRKD3ABL1 | |
| SCHEMBL6015657 | 0.75 | KDR (0.73) | KDRNTRK1RAB9APRKD3ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |