Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792102 | 0.83 | TSHR (0.39) | CYP2C19TSHRHRH1HTR2ATAAR1 | |
| SCHEMBL3804767 | 0.81 | CYP2C19 (0.37) | CYP2C19TSHRHRH1HTR2ATAAR1 | |
| SCHEMBL5560718 | 0.79 | TRPA1 (0.44) | CYP2C19HRH1SMN1; SMN2RIPK1KDM4E | |
| SCHEMBL28644783 | 0.79 | HRH1 (0.56) | CYP2C19TSHRHRH1HTR2ATAAR1 | |
| SCHEMBL6705012 | 0.79 | CYP2C19 (0.36) | CYP2C19HRH1HTR2ATAAR1SMN1; SMN2 | |
| SCHEMBL3022300 | 0.79 | AOC3 (0.42) | CYP2C19HRH1HTR2ATAAR1RIPK1 | |
| SCHEMBL8014725 | 0.78 | POLB (0.41) | CYP2C19HRH1HTR2ATAAR1RIPK1 | |
| SCHEMBL5561239 | 0.78 | CYP2C19 (0.35) | CYP2C19HRH1HTR2ASMN1; SMN2RIPK1 | |
| SCHEMBL8465661 | 0.78 | ACP3 (0.44) | SMN1; SMN2CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL4819524 | 0.76 | POLB (0.41) | HRH1HTR2ARIPK1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064179-B1 | Peg-based macromonomers, chemically inert polymers prepared therefrom and the use of these polymers for organic synthesis and enzyme reactions | CARLSBERG A/S (DK) | 2006-06-20 | — | — | US | disclosed |
| EP-1137690-A2 | PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS | Carlsberg A/S (DK) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000018823-A2 | PEG-BASED MACROMONOMERS, CHEMICALLY INERT POLYMERS PREPARED THEREFROM AND THE USE OF THESE POLYMERS FOR ORGANIC SYNTHESIS AND ENZYME REACTIONS | CARLSBERG A/S (DK) | 2000-04-06 | — | — | WO | disclosed |