Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.91 |
| ▸ | CHRM3 | P20309 | 20/20 | 0.91 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845377 | 1.00 | ADRB2 (0.91) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2845370 | 1.00 | ADRB2 (0.91) | ADRB2CHRM3CHRM2 | |
| SCHEMBL5651678 | 0.95 | ADRB2 (1.00) | ADRB2CHRM3CHRM2 | |
| SCHEMBL5651657 | 0.95 | ADRB2 (1.00) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2847514 | 0.92 | CHRM3 (0.88) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2847528 | 0.92 | CHRM3 (0.88) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2843799 | 0.92 | ADRB2 (0.88) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2843790 | 0.92 | ADRB2 (0.88) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2846744 | 0.92 | ADRB2 (0.87) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2846751 | 0.92 | ADRB2 (0.87) | ADRB2CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615889-A2 | BIPHENYL DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | Theravance Inc (US) | 2006-01-18 | — | — | EP | claimed |
| WO-2004074246-A2 | BIPHENYL DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | THERAVANCE INC. (US) | 2004-09-02 | — | — | WO | claimed |