Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016954 | 0.91 | F10 (0.55) | F10F2NPY1RALDH1A1 | |
| SCHEMBL3370984 | 0.90 | RAB9A (0.40) | F10F2ALDH1A1LMNANPC1 | |
| SCHEMBL1380548 | 0.80 | F10 (0.65) | F10F2 | |
| SCHEMBL3371312 | 0.79 | F10 (0.45) | F10F2ALDH1A1LMNANPC1 | |
| SCHEMBL1383452 | 0.79 | F10 (0.63) | F10F2 | |
| SCHEMBL6016870 | 0.79 | F10 (0.39) | F10F2ALDH1A1 | |
| SCHEMBL6016887 | 0.78 | F10 (0.50) | F10F2ALDH1A1 | |
| SCHEMBL1379117 | 0.78 | F10 (0.61) | F10F2 | |
| SCHEMBL3371687 | 0.78 | RAB9A (0.45) | F10F2ALDH1A1LMNANPC1 | |
| SCHEMBL3370092 | 0.77 | RAB9A (0.45) | F10F2ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |