Methacrylic Acid

Methacrylic Acid

SCHEMBL6016973

C=C(C)C(=O)O.c1ccc(-c2ccccc2OCC2CO2)cc1

nearest known ligand 0.52

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
GLA P06280 1/20 0.52
KDM4E B2RXH2 13/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 3/20 0.46
HTT P42858 1/20 0.46
BLM P54132 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
KMT2A Q03164 4/20 0.45
GAA P10253 1/20 0.45
MEN1 O00255 3/20 0.45
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL21811400 1.00 ALDH1A1 (0.52) ALDH1A1GLAKDM4ESMN1; SMN2POLB
SCHEMBL29422796 0.86 ALDH1A1 (0.64) ALDH1A1GLASMN1; SMN2HTTL3MBTL1
SCHEMBL623648 0.86 ALDH1A1 (0.64) ALDH1A1GLASMN1; SMN2HTTL3MBTL1
SCHEMBL8993129 0.86 ALDH1A1 (0.64) ALDH1A1GLASMN1; SMN2HTTL3MBTL1
Acrylic Acid SCHEMBL424870 0.85 ALDH1A1 (0.50) ALDH1A1GLAKDM4ESMN1; SMN2HTT
Water SCHEMBL22325690 0.84 ALDH1A1 (0.62) ALDH1A1GLASMN1; SMN2HTTL3MBTL1
SCHEMBL17422018 0.83 ALDH1A1 (0.60) ALDH1A1GLASMN1; SMN2L3MBTL1TDP1
SCHEMBL9999241 0.82 ALDH1A1 (0.48) ALDH1A1GLAKDM4ESMN1; SMN2L3MBTL1
Methacrylic Acid SCHEMBL7198324 0.82 ALDH1A1 (0.50) ALDH1A1GLAKDM4ETDP1KMT2A
2-Phenylphenol SCHEMBL9623287 0.82 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2TDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060088257-A1 Photosensitive resin composition for optical waveguides, and optical waveguide and manufacturing method thereof JSR CORPORATION (JP) 2006-04-27 US disclosed
US-5164464-A Liquid crystalline polymers, acrylated epoxy resins THE DOW CHEMICAL COMPANY (US) 1992-11-17 US disclosed
US-5066750-A Addition polymers with pendant phenyl groups which can be oriented like liquid crystals THE DOW CHEMICAL COMPANY (US) 1991-11-19 US disclosed
US-4962163-A ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS THE DOW CHEMICAL COMPANY (US) 1990-10-09 US disclosed