Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4829461 | 0.90 | HRH4 (0.52) | HRH4IDH2IKBKBEHMT2EHMT1 | |
| SCHEMBL11482610 | 0.86 | PDE4A (0.56) | HRH4PDE4ANUDT1EPHX2 | |
| SCHEMBL27589550 | 0.84 | HRH4 (0.50) | HRH4IDH2IKBKBEHMT2EHMT1 | |
| SCHEMBL27628560 | 0.80 | PDE4A (0.50) | HRH4PDE4ANUDT1 | |
| SCHEMBL5031353 | 0.79 | PDE4A (0.49) | HRH4PDE4AIDH2IKBKBNUDT1 | |
| SCHEMBL5553458 | 0.78 | HRH4 (0.41) | HRH4IDH2IKBKBEHMT2EHMT1 | |
| SCHEMBL10706738 | 0.76 | NUDT1 (0.43) | HRH4PDE4ANUDT1 | |
| SCHEMBL6919383 | 0.76 | PDE4A (0.46) | PDE4ANUDT1 | |
| Cyromazine SCHEMBL27231 | 0.72 | NUDT1 (0.43) | HRH4PDE4ANUDT1 | |
| Cyromazine SCHEMBL10832935 | 0.72 | NUDT1 (0.43) | HRH4PDE4ANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1697831-A | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS INC (US) | 2005-11-16 | — | — | CN | claimed |
| US-7112587-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-09-26 | — | — | US | disclosed |