Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9229280 | 0.98 | EGFR (0.42) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL8874014 | 0.76 | EGFR (0.58) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL31554558 | 0.68 | EGFR (0.46) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL29756110 | 0.68 | EGFR (0.39) | EGFRPIK3CDPIK3CAIMPDH2 | |
| SCHEMBL30326091 | 0.68 | EGFR (0.39) | EGFRPIK3CDPIK3CAIMPDH2 | |
| SCHEMBL6017066 | 0.68 | KDM4E (0.44) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL29551582 | 0.67 | EGFR (0.48) | EGFRPIK3CDPIK3CAFGFR4 | |
| SCHEMBL2190665 | 0.67 | EGFR (0.48) | EGFRPIK3CDPIK3CAFGFR4TDO2 | |
| SCHEMBL28181384 | 0.67 | EGFR (0.48) | EGFRPIK3CDPIK3CAFGFR4 | |
| SCHEMBL7222157 | 0.67 | EGFR (0.59) | EGFRPIK3CDPIK3CAFGFR4TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638567-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE5 INHIBITOR FOR THE TREATMENT OF LUNG DISEASES | ALTANA Pharma AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| EP-1628682-A2 | COMPOSITION COMPRISING A PDE4 INHIBITOR AND A PDE5 INHIBITOR | ALTANA Pharma AG (DE) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004110450-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE5 INHIBITOR FOR THE TREATMENT OF LUNG DISEASES | ALTANA PHARMA AG (DE) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004103407-A2 | COMPOSITION COMPRISING A PDE4 INHIBITOR AND A PDE5 INHIBITOR | ALTANA PHARMA AG (DE) | 2004-12-02 | — | — | WO | disclosed |