Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 9/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9229288 | 0.98 | KDM4E (0.42) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL30035692 | 0.81 | GRIN2D (0.44) | KDM4EMAPTMEN1KMT2AEGFR | |
| SCHEMBL8874014 | 0.75 | EGFR (0.58) | EGFRTDO2PIK3CDPIK3CAFGFR4 | |
| SCHEMBL4233464 | 0.70 | MAPT (0.46) | KDM4EMAPTEGFRTDO2ALDH1A1 | |
| SCHEMBL27461853 | 0.69 | EGFR (0.44) | MAPTEGFRTDO2PIK3CDPIK3CA | |
| SCHEMBL9039584 | 0.69 | EGFR (0.41) | EGFRTDO2PIK3CDPIK3CAFGFR4 | |
| SCHEMBL9039580 | 0.69 | EGFR (0.41) | EGFRTDO2PIK3CDPIK3CAFGFR4 | |
| SCHEMBL30031292 | 0.68 | ALDH1A1 (0.50) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5374927 | 0.68 | ALDH1A1 (0.50) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7687471 | 0.68 | KMO (0.45) | EGFRLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638567-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE5 INHIBITOR FOR THE TREATMENT OF LUNG DISEASES | ALTANA Pharma AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| EP-1628682-A2 | COMPOSITION COMPRISING A PDE4 INHIBITOR AND A PDE5 INHIBITOR | ALTANA Pharma AG (DE) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004110450-A1 | COMPOSITION COMPRISING A PULMONARY SURFACTANT AND A PDE5 INHIBITOR FOR THE TREATMENT OF LUNG DISEASES | ALTANA PHARMA AG (DE) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004103407-A2 | COMPOSITION COMPRISING A PDE4 INHIBITOR AND A PDE5 INHIBITOR | ALTANA PHARMA AG (DE) | 2004-12-02 | — | — | WO | disclosed |