Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 0.44 |
| ▸ | EHMT1 | Q9H9B1 | 10/20 | 0.44 |
| ▸ | BCL6 | P41182 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207770 | 0.90 | EHMT2 (0.44) | EHMT2EHMT1BCL6KDM1ARCOR1 | |
| SCHEMBL5033403 | 0.79 | MAPT (0.45) | EHMT2EHMT1BCL6PDE4APDE4B | |
| SCHEMBL6016637 | 0.78 | EHMT2 (0.48) | EHMT2EHMT1BCL6KDM1ARCOR1 | |
| SCHEMBL6017083 | 0.77 | BCL6 (0.47) | EHMT2EHMT1BCL6KDM1ARCOR1 | |
| SCHEMBL4839209 | 0.76 | EHMT2 (0.50) | EHMT2EHMT1BCL6KDM1ARCOR1 | |
| SCHEMBL14274163 | 0.76 | MAPT (0.45) | EHMT2EHMT1BCL6 | |
| SCHEMBL5457407 | 0.71 | EHMT2 (0.53) | EHMT2EHMT1BCL6KDM1ARCOR1 | |
| SCHEMBL4838760 | 0.71 | GALR1 (0.41) | EHMT2EHMT1BCL6PDGFRBPDGFRA | |
| SCHEMBL5029049 | 0.69 | MAPT (0.48) | BCL6 | |
| SCHEMBL5032475 | 0.68 | EHMT2 (0.49) | EHMT2EHMT1BCL6ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132423-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2006-11-07 | — | — | US | disclosed |