SCHEMBL6207770

SCHEMBL6207770

COc1ccc(N(C)c2nc(NC3CCN(C)CC3)nc(OC3CC4CCC3C4)n2)cc1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 14/20 0.44
EHMT1 Q9H9B1 12/20 0.44
BCL6 P41182 1/20 0.39
KDM1A O60341 2/20 0.37
RCOR1 Q9UKL0 2/20 0.37
PDGFRB P09619 2/20 0.36
PDGFRA P16234 2/20 0.36
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35
TUBA3E Q6PEY2 1/20 0.35
TUBA1A Q71U36 1/20 0.35
TUBA1C Q9BQE3 1/20 0.35
TUBB6 Q9BUF5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6017073 0.90 EHMT2 (0.44) EHMT2EHMT1BCL6KDM1ARCOR1
SCHEMBL5457407 0.82 EHMT2 (0.53) EHMT2EHMT1BCL6KDM1ARCOR1
SCHEMBL4838760 0.79 GALR1 (0.41) EHMT2EHMT1BCL6PDGFRBPDGFRA
SCHEMBL4837987 0.76 EHMT2 (0.50) EHMT2EHMT1BCL6
SCHEMBL14274164 0.76 GALR1 (0.41) EHMT2EHMT1BCL6
SCHEMBL5420636 0.73 EHMT2 (0.44) EHMT2EHMT1BCL6
Citric Acid SCHEMBL6016965 0.72 EHMT2 (0.43) EHMT2EHMT1BCL6KDM1ARCOR1
SCHEMBL4832215 0.71 EHMT2 (0.44) EHMT2EHMT1BCL6
SCHEMBL5033403 0.71 MAPT (0.45) EHMT2EHMT1BCL6PDGFRBPDGFRA
SCHEMBL4839842 0.70 EHMT2 (0.43) EHMT2EHMT1BCL6PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560817-A1 METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS Reddy US Therapeutics, Inc. (US) 2005-08-10 EP claimed
WO-2004026844-A1 METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS REDDY US THERAPEUTICS, INC. (US) 2004-04-01 WO claimed