⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560078 | 0.79 | — | — | |
| SCHEMBL7964375 | 0.74 | BRD4 (0.34) | — | |
| SCHEMBL5328708 | 0.69 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL30292163 | 0.69 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL11829608 | 0.68 | — | — | |
| SCHEMBL10866258 | 0.66 | — | — | |
| SCHEMBL3092149 | 0.65 | — | — | |
| SCHEMBL6838846 | 0.62 | — | — | |
| SCHEMBL7799915 | 0.62 | — | — | |
| SCHEMBL5924132 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041286-B | Preparation method of 3, 3-difluoro-4-hydroxy-5- (hydroxymethyl) dihydrofuran-2 (3H) -ketone | 苏州永健生物医药有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-116041286-A | Preparation method of 3, 3-difluoro-4-hydroxy-5- (hydroxymethyl) dihydrofuran-2 (3H) -ketone | 苏州永健生物医药有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-116041286-B | Preparation method of 3, 3-difluoro-4-hydroxy-5- (hydroxymethyl) dihydrofuran-2 (3H) -ketone | 苏州永健生物医药有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-116041286-B | Preparation method of 3, 3-difluoro-4-hydroxy-5- (hydroxymethyl) dihydrofuran-2 (3H) -ketone | 苏州永健生物医药有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-116041286-A | Preparation method of 3, 3-difluoro-4-hydroxy-5- (hydroxymethyl) dihydrofuran-2 (3H) -ketone | 苏州永健生物医药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-116041286-A | Preparation method of 3, 3-difluoro-4-hydroxy-5- (hydroxymethyl) dihydrofuran-2 (3H) -ketone | 苏州永健生物医药有限公司 | 2023-05-02 | — | — | CN | disclosed |
| EP-1660080-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1478634-A4 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS INC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2005016340-A1 | FURANONE DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | disclosed |
| EP-1478634-A1 | FURANONE DERIVATIVES | Galileo Pharmaceuticals, Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003064403-A1 | FURANONE DERIVATIVES | GALILEO LABORATORIES, INC. (US) | 2003-08-07 | — | — | WO | disclosed |