Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961617 | 0.68 | GAA (0.40) | BRD4ALDH1A1KMT2ATSHRHSD17B10 | |
| SCHEMBL3112694 | 0.68 | ALDH1A1 (0.35) | BRD4CYP1A2HIF1AALDH1A1PPM1B | |
| SCHEMBL2709751 | 0.65 | SLC6A3 (0.34) | BRD4ALDH1A1KMT2AMAPK1HSD17B10 | |
| SCHEMBL31079450 | 0.64 | BRD4 (0.32) | BRD4CYP1A2HIF1A | |
| SCHEMBL2597463 | 0.64 | BRD4 (0.45) | BRD4CYP1A2HIF1AALDH1A1MMP2 | |
| SCHEMBL8531715 | 0.64 | CA1 (0.43) | BRD4CYP1A2HIF1APPM1BPTPN1 | |
| SCHEMBL12104210 | 0.64 | CA1 (0.43) | BRD4CYP1A2HIF1APPM1BPTPN1 | |
| SCHEMBL21389240 | 0.64 | CA1 (0.43) | BRD4CYP1A2HIF1APPM1BPTPN1 | |
| SCHEMBL7964378 | 0.63 | ALDH1A1 (0.41) | BRD4CYP1A2HIF1AALDH1A1CYP2D6 | |
| SCHEMBL30989220 | 0.63 | ALDH1A1 (0.38) | BRD4ALDH1A1MMP2ANPEPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |