Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.59 |
| ▸ | CCR5 | P51681 | 3/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017065 | 0.84 | CCR3 (0.75) | CCR3CCR5CPT1APIK3CDPIK3CB | |
| SCHEMBL6017132 | 0.82 | CCR3 (0.38) | CCR3CCR5CYP11B1CYP11B2DRD2 | |
| SCHEMBL5393280 | 0.75 | CCR3 (1.00) | CCR3CPT1APIK3CDPIK3CBPDE10A | |
| SCHEMBL6017337 | 0.72 | CCR3 (0.59) | CCR3CCR5PIK3CDPIK3CBPDE10A | |
| SCHEMBL5377784 | 0.70 | CCR3 (1.00) | CCR3CPT1AHTR2BDRD2DRD3 | |
| SCHEMBL6344442 | 0.68 | CCR3 (0.54) | CCR3CCR5CYP11B1CYP11B2HTR2B | |
| SCHEMBL6017180 | 0.68 | CCR3 (0.54) | CCR3CCR5CYP11B1CYP11B2KCNH2 | |
| SCHEMBL5393257 | 0.67 | CCR3 (0.65) | CCR3CPT1ADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL5382308 | 0.67 | CCR3 (0.64) | CCR3CPT1ADRD2DRD4DRD3 | |
| SCHEMBL6017254 | 0.64 | CCR3 (0.49) | CCR3CCR5CYP11B1CYP11B2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648888-A1 | N-(HETEROBICYCLOALKANES)-SUBSTITUTED INDOLES OR HETERODERIVATIVES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005005425-A1 | N-(HETEROBICYCLOALKANES)-SUBTITUTED INDOLES- OR HETERODERIVATIVES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | WO | disclosed |
| EP-1496058-A1 | Novel N-(heterobicycloalkanes)-substituted Indoles or heteroderivatives thereof | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-01-12 | — | — | EP | disclosed |