Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.54 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017180 | 0.88 | CCR3 (0.54) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL6017337 | 0.86 | CCR3 (0.59) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL6017065 | 0.85 | CCR3 (0.75) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL6017254 | 0.78 | CCR3 (0.49) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL3289951 | 0.71 | CCR3 (0.79) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL5742427 | 0.71 | CCR3 (0.76) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL6017085 | 0.71 | CCR3 (0.44) | CCR3SLC6A2SLC6A4SLC6A3CYP11B1 | |
| SCHEMBL5383638 | 0.70 | CCR3 (0.74) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL5377784 | 0.70 | CCR3 (1.00) | CCR3HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL6017398 | 0.68 | CCR3 (0.59) | CCR3DRD2DRD3HTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014782-A1 | Novel n-(heterobicycloalkanes)-substituted indoles-or heteroderivatives thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-01-20 | — | — | US | disclosed |
| EP-1496058-A1 | Novel N-(heterobicycloalkanes)-substituted Indoles or heteroderivatives thereof | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014782-A1 | Novel n-(heterobicycloalkanes)-substituted indoles-or heteroderivatives thereof | CCR3, CCR1, CCRL2 | CCR3 1/4885HTR1A 157/4885DRD2 465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.