Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014502 | 0.93 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL4014343 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL3935756 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL2827198 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL951538 | 0.76 | KMT2A (0.59) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL304546 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL16095464 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL3722611 | 0.76 | SYK (0.50) | SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL9008880 | 0.76 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9AHTTMEN1 | |
| SCHEMBL30306894 | 0.75 | HSD11B1 (0.50) | MEN1KMT2AL3MBTL1GPR119STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720874-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | Bioaxone Therapeutique Inc. (CA) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005080394-A1 | 4-SUBSTITUTED PIPERIDINE DERIVATIVES | BIOAXONE THERAPEUTIQUE INC. (CA) | 2005-09-01 | — | — | WO | disclosed |