SCHEMBL60175

SCHEMBL60175

Nc1nc2c(ncn2CCC(CO)CF)c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TK1 P04183 2/20 0.63
BLM P54132 2/20 0.60
MEN1 O00255 1/20 0.60
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
CYP3A4 P08684 1/20 0.60
NFKB1 P19838 1/20 0.60
VCP P55072 1/20 0.60
KMT2A Q03164 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
HIF1A Q16665 1/20 0.60
PNP P00491 6/20 0.56
USP2 O75604 1/20 0.56
TSHR P16473 1/20 0.56
EDNRA P25101 1/20 0.56
HTR2A P28223 1/20 0.56
RECQL P46063 1/20 0.56
HBB P68871 1/20 0.56
HSD17B10 Q99714 1/20 0.56
HPRT1 P00492 9/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371675 1.00 TK1 (0.63) TK1BLMMEN1ALDH1A1LMNA
Penciclovir SCHEMBL3495 0.94 TK1 (0.70) TK1BLMMEN1ALDH1A1LMNA
Penciclovir SCHEMBL583037 0.93 TK1 (0.69) TK1BLMMEN1ALDH1A1LMNA
Penciclovir SCHEMBL7192792 0.93 TK1 (0.69) TK1BLMMEN1ALDH1A1LMNA
Penciclovir SCHEMBL10414021 0.93 TK1 (0.69) TK1BLMMEN1ALDH1A1LMNA
Penciclovir SCHEMBL28339260 0.92 TK1 (0.65) TK1BLMMEN1ALDH1A1LMNA
SCHEMBL6268539 0.89 TK1 (0.65) TK1BLMMEN1ALDH1A1LMNA
Penciclovir SCHEMBL454090 0.89 HPRT1 (0.66) TK1BLMMEN1ALDH1A1LMNA
SCHEMBL10508817 0.89 TK1 (0.68) TK1BLMMEN1ALDH1A1LMNA
Penciclovir SCHEMBL4240104 0.89 HPRT1 (0.66) TK1BLMMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110730908-B Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified versions thereof and related methods 朱诺治疗学股份有限公司 2025-01-21 CN claimed
US-20230190796-A1 ENGINEERED CELLS EXPRESSING PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) OR A MODIFIED FORM THEREOF AND RELATED METHODS JUNO THERAPEUTICS, INC. (US) 2023-06-22 US claimed
CN-114807041-A Myocardial cell for pharmacokinetic research and preparation method thereof 南京艾尔普再生医学科技有限公司 2022-07-29 CN claimed
US-11253611-B2 Thymidine kinase diagnostic assay for gene therapy applications Genvivo, Inc. (US) 2022-02-22 US claimed
EP-3607319-A1 ENGINEERED CELLS EXPRESSING PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) OR A MODIFIED FORM THEREOF AND RELATED METHODS Juno Therapeutics, Inc. (US) 2020-02-12 EP claimed
CN-110730908-A Engineered cells expressing Prostate Specific Membrane Antigen (PSMA) or modified forms thereof and related methods 朱诺治疗学股份有限公司 2020-01-24 CN claimed
US-20190328904-A1 THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS Genvivo, Inc. 2019-10-31 US claimed
US-10350302-B2 Thymidine kinase diagnostic assay for gene therapy applications Genvivo, Inc. (US) 2019-07-16 US claimed
EP-2967078-B1 THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS GENVIVO INC (US) 2018-10-17 EP claimed
WO-2018187791-A1 ENGINEERED CELLS EXPRESSING PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) OR A MODIFIED FORM THEREOF AND RELATED METHODS JUNO THERAPEUTICS, INC (US) 2018-10-11 WO claimed
US-20140294772-A1 THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS EPEIUS BIOTECHNOLOGIES CORPORATION (US) 2014-10-02 US claimed
WO-2014153205-A1 THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS EPEIUS BIOTECHNOLOGIES CORPORATION (US) 2014-09-25 WO claimed
US-20140228248-A1 METHODS AND COMPOSITIONS FOR DETECTING INFECTIONS BIOMED VALLEY DISCOVERIES, INC. (US) 2014-08-14 US claimed
WO-2013048952-A1 METHODS AND COMPOSITIONS FOR DETECTING INFECTIONS BIOMED VALLEY DISCOVERIES, INC. (US) 2013-04-04 WO claimed
US-8357486-B2 Methods and compositions for detection of bacteria and treatment of diseases and disorders GENELUX CORPORATION (US) 2013-01-22 US claimed
US-8343509-B2 Methods and compositions for detection of bacteria and treatment of diseases and disorders GENELUX CORPORATION (US) 2013-01-01 US claimed
US-20120020883-A1 Methods and compositions for detection of bacteria and treatment of diseases and disorders GENELUX CORPORATION 2012-01-26 US claimed
EP-2242516-A1 METHODS AND COMPOSITIONS FOR DETECTION OF BACTERIA AND TREATMENT OF DISEASES AND DISORDERS Genelux Corporation (US) 2010-10-27 EP claimed
WO-2009126189-A1 METHODS AND COMPOSITIONS FOR DETECTION OF BACTERIA AND TREATMENT OF DISEASES AND DISORDERS GENELUX CORPORATION (US) 2009-10-15 WO claimed
US-20090180955-A1 Methods and compositions for detection of bacteria and treatment of diseases and disorders GENELUX CORPORATION 2009-07-16 US claimed