SCHEMBL6017532

SCHEMBL6017532

CC(Cc1cccc(CC(=O)O)c1)NCC(O[Si](C)(C)C(C)(C)C)c1ccc(O)c(NS(C)(=O)=O)c1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 12/20 0.58
ADRB3 P13945 8/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5037091 1.00 ADRB2 (0.58) ADRB2ADRB3
SCHEMBL5037090 1.00 ADRB2 (0.58) ADRB2ADRB3
SCHEMBL14204723 0.94 ADRB2 (0.56) ADRB2ADRB3
SCHEMBL5041970 0.93 ADRB2 (0.48) ADRB2ADRB3
SCHEMBL5041964 0.93 ADRB2 (0.48) ADRB2ADRB3
SCHEMBL5034329 0.88 ADRB2 (0.47) ADRB2ADRB3
SCHEMBL5034327 0.88 ADRB2 (0.47) ADRB2ADRB3
SCHEMBL3629555 0.88 ADRB2 (0.47) ADRB2ADRB3
SCHEMBL3629559 0.88 ADRB2 (0.47) ADRB2ADRB3
SCHEMBL5567251 0.87 ADRB2 (0.49) ADRB2ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1708992-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES Pfizer Limited (GB) 2006-10-11 EP disclosed
WO-2005080324-A1 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LIMITED (GB) 2005-09-01 WO disclosed