Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.54 |
| ▸ | SHBG | P04278 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017581 | 1.00 | CYP3A4 (0.78) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL13069730 | 0.88 | HIF1A (1.00) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL3406165 | 0.88 | HIF1A (0.85) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL3395657 | 0.88 | HIF1A (1.00) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL3395660 | 0.88 | HIF1A (1.00) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL8637937 | 0.88 | HIF1A (1.00) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL17714998 | 0.88 | HIF1A (1.00) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL9623707 | 0.87 | CYP3A4 (0.71) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL9623710 | 0.87 | CYP3A4 (0.71) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR | |
| SCHEMBL10974542 | 0.87 | CYP3A4 (0.71) | CYP3A4HIF1ACYP2C9ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7018648-B2 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20050256051-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | THE POPULATION COUNCIL, INC. (US) | 2005-11-17 | — | — | US | disclosed |
| US-20050100586-A1 | Transdermal device for administering testosterone or one of the derivatives thereof | PIERRE FABRE MEDICAMENT (FR) | 2005-05-12 | — | — | US | disclosed |
| EP-1178806-B1 | TRANSDERMAL DEVICE FOR THE APPLICATION OF TESTOSTERONE OR ONE OF THE DERIVATIVES THEREOF | PF MEDICAMENT (FR) | 2004-09-01 | — | — | EP | disclosed |
| US-6767902-B2 | Androgen as a male contraceptive and non-contraceptive androgen replacement | THE POPULATION COUNCIL, INC. | 2004-07-27 | — | — | US | disclosed |
| US-20040132698-A1 | Androgen as a male contraceptive and non-contraceptive androgen replacement | MOO-YOUNG ALFRED J (US) | 2004-07-08 | — | — | US | disclosed |
| US-20040126418-A1 | Transdermal administration of MENT | THE POPULATION COUNCIL, INC. | 2004-07-01 | — | — | US | disclosed |
| US-20030096739-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | POPULATION COUNCIL, INC., THE | 2003-05-22 | — | — | US | disclosed |
| US-20020193359-A1 | Administering to a non-sterile male subject a predetermined amount of an androgen which is sufficient to render male subject reversibly sterile for a predetermined period of time | POPULATION COUNCIL, INC., THE | 2002-12-19 | — | — | US | disclosed |
| US-20020012694-A1 | TRANSDERMAL ADMINISTRATION OF MENT | POPULATION COUNCIL, INC., THE, A CORP. OF NY | 2002-01-31 | — | — | US | disclosed |
| US-5342834-A | Administering testosterone derivatives | THE POPULATION COUNCIL, INC. (US) | 1994-08-30 | — | — | US | disclosed |