Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424234 | 0.87 | NR3C1 (0.30) | — | |
| SCHEMBL3424991 | 0.86 | — | — | |
| SCHEMBL13183166 | 0.78 | — | — | |
| SCHEMBL3429546 | 0.77 | AKR1B1 (0.33) | — | |
| SCHEMBL3429593 | 0.76 | NR3C1 (0.32) | — | |
| SCHEMBL3426803 | 0.75 | AKR1B1 (0.33) | — | |
| SCHEMBL3424846 | 0.75 | NR3C1 (0.51) | — | |
| SCHEMBL13183165 | 0.68 | NR3C1 (0.41) | — | |
| SCHEMBL13183167 | 0.65 | AKR1B1 (0.33) | — | |
| SCHEMBL3429053 | 0.63 | AKR1B1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727813-A1 | 2-PROPANOL AND 2-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005090336-A1 | 2-PROPANOL AND 2-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | WO | disclosed |