SCHEMBL6017891

SCHEMBL6017891

CC(=O)c1ccco1.CC1=C(O)C(=O)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
KMT2A Q03164 3/20 0.39
POLB P06746 3/20 0.39
LMNA P02545 2/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
PTPN1 P18031 1/20 0.39
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 5/20 0.38
GAA P10253 3/20 0.38
RAB9A P51151 3/20 0.38
TP53 P04637 2/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
APEX1 P27695 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAPK1 P28482 1/20 0.38
MEN1 O00255 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43960 0.78
SCHEMBL27777913 0.78 CES2 (0.65) CES2CES1KMT2APOLBLMNA
SCHEMBL27670963 0.76
Methane SCHEMBL27898477 0.76
Water SCHEMBL27897236 0.76
SCHEMBL27514702 0.76 CES2 (0.62) CES2CES1KMT2APOLBLMNA
Formaldehyde SCHEMBL28759882 0.74 CES2 (0.60) CES2CES1KMT2APOLBLMNA
Bromide SCHEMBL28275345 0.74 CES2 (0.60) CES2CES1KMT2APOLBLMNA
Acetic Acid SCHEMBL27532060 0.74 CES2 (0.60) CES2CES1KMT2APOLBLMNA
Acetamide SCHEMBL29005832 0.73 CES2 (0.58) CES2CES1KMT2APOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661465-A1 Fat-based confections comprising flavor components Mars Incorporated (US) 2006-05-31 EP disclosed