SCHEMBL6017927

SCHEMBL6017927

O=C(N[C@@H](CCCNCc1ccccn1)C(=O)NCCc1c[nH]c2ccccc12)c1ccc(CNCc2ccccn2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.49
KMT2A Q03164 5/20 0.47
MEN1 O00255 3/20 0.47
CDK4 P11802 1/20 0.47
CCND1 P24385 1/20 0.47
SNCA P37840 1/20 0.47
HDAC3 O15379 5/20 0.46
HDAC1 Q13547 5/20 0.46
HDAC2 Q92769 5/20 0.46
NCOR2 Q9Y618 4/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
SIRT1 Q96EB6 3/20 0.45
HDAC6 Q9UBN7 2/20 0.45
ACHE P22303 1/20 0.45
NAMPT P43490 1/20 0.45
HDAC4 P56524 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6657565 0.90 CXCR4 (0.47) CXCR4KMT2AMEN1CDK4CCND1
Tryptamine SCHEMBL6670107 0.88 CXCR4 (0.47) CXCR4KMT2ACDK4CCND1SNCA
SCHEMBL27566493 0.84 CXCR4 (0.55) CXCR4KMT2AMEN1NPC1RAB9A
SCHEMBL6018215 0.84 CXCR4 (0.55) CXCR4KMT2AMEN1NPC1RAB9A
SCHEMBL6657094 0.82 MMP2 (0.44) KMT2AMEN1CDK4CCND1HDAC3
SCHEMBL6019208 0.82 MMP2 (0.42) KMT2AMEN1MMP2MMP9MMP8
SCHEMBL27616554 0.82 CXCR4 (0.54) CXCR4KMT2ANPC1RAB9A
SCHEMBL6018126 0.82 CXCR4 (0.54) CXCR4KMT2ANPC1RAB9A
SCHEMBL6654299 0.80 CXCR4 (0.47) CXCR4KMT2AMEN1CDK4CCND1
SCHEMBL6018244 0.79 CXCR4 (0.51) CXCR4KMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098215-B2 Nitrogenous compounds and antiviral drugs containing the same KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 2006-08-29 US disclosed