Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 5/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.50 |
| ▸ | TEK | Q02763 | 10/20 | 0.49 |
| ▸ | KDR | P35968 | 9/20 | 0.49 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036539 | 0.93 | ENPP3 (0.50) | ENPP3ENPP1ENPP2TEKKDR | |
| SCHEMBL5035957 | 0.85 | ENPP3 (0.46) | ENPP3ENPP1ENPP2TEKKDR | |
| SCHEMBL5036578 | 0.85 | MTOR (0.52) | ENPP3ENPP1ENPP2TEKKDR | |
| SCHEMBL5043065 | 0.85 | NPC1 (0.44) | ENPP3ENPP1ENPP2TEKKDR | |
| SCHEMBL5033465 | 0.85 | CNR1 (0.43) | ENPP3ENPP1ENPP2TEKKDR | |
| SCHEMBL5042876 | 0.83 | EPHX1 (0.42) | ENPP3ENPP1ENPP2TEKKDR | |
| SCHEMBL5036480 | 0.82 | NPC1 (0.53) | ENPP3ENPP1ENPP2CA12CA9 | |
| SCHEMBL5042858 | 0.82 | NPC1 (0.50) | ENPP3ENPP1ENPP2TEKKDR | |
| SCHEMBL5041053 | 0.82 | NPC1 (0.52) | ENPP3ENPP1ENPP2CA12CA9 | |
| SCHEMBL5033714 | 0.82 | NPC1 (0.54) | ENPP3ENPP1ENPP2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041668-B2 | Substituted benzimidazole compounds and their use for the treatment of cancer | AVENTIS PHARMA S.A. (FR) | 2006-05-09 | — | — | US | claimed |