Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3955699 | 0.90 | PTGER4 (0.51) | PTGER4TP53MAPTSIRT2SIRT1 | |
| SCHEMBL1626658 | 0.87 | PTGER4 (0.64) | PTGER4TP53MAPTSIRT2SIRT1 | |
| SCHEMBL7594246 | 0.85 | PTGER4 (0.48) | PTGER4TP53MAPTSIRT2SIRT1 | |
| SCHEMBL23844020 | 0.84 | PTGER4 (0.49) | PTGER4TP53MAPTNTRK1NTRK2 | |
| SCHEMBL7594142 | 0.84 | PTGER4 (0.49) | PTGER4TP53MAPTNTRK1NTRK2 | |
| SCHEMBL6018506 | 0.83 | PTGER4 (0.52) | PTGER4TP53MAPTNTRK1NTRK2 | |
| SCHEMBL7594108 | 0.82 | PTGER4 (0.50) | PTGER4TP53SIRT2SIRT1NTRK1 | |
| SCHEMBL7595033 | 0.82 | PTGER4 (0.48) | PTGER4TP53SIRT2SIRT1NTRK1 | |
| SCHEMBL1626075 | 0.81 | TP53 (0.44) | PTGER4TP53MAPTSIRT2SIRT1 | |
| SCHEMBL21470297 | 0.80 | PTGER4 (0.49) | PTGER4TP53NTRK1NTRK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666480-A1 | Aryl or Heteroaryl Fused Imidazole Compounds as intermediates for Anti-Inflammatory And Analgesic Agents. | PFIZER PHARMACEUTICALS INC. (JP) | 2006-06-07 | — | — | EP | disclosed |