Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594108 | 0.92 | PTGER4 (0.50) | PTGER4KMT2AAGTR2AGTR1SIRT2 | |
| SCHEMBL7594246 | 0.86 | PTGER4 (0.48) | PTGER4KMT2AMEN1AGTR2AGTR1 | |
| SCHEMBL3955699 | 0.83 | PTGER4 (0.51) | PTGER4KMT2AMEN1AGTR2AGTR1 | |
| SCHEMBL6018725 | 0.82 | PTGER4 (0.48) | PTGER4KMT2AMEN1AGTR2AGTR1 | |
| SCHEMBL23844020 | 0.82 | PTGER4 (0.49) | PTGER4KMT2AMEN1AGTR2AGTR1 | |
| SCHEMBL7594142 | 0.82 | PTGER4 (0.49) | PTGER4KMT2AMEN1AGTR2AGTR1 | |
| SCHEMBL6018506 | 0.81 | PTGER4 (0.52) | PTGER4KMT2AMEN1AGTR2AGTR1 | |
| SCHEMBL1625825 | 0.81 | PTGER4 (0.42) | PTGER4KMT2AMEN1SIRT2SIRT1 | |
| SCHEMBL1626764 | 0.78 | MEN1 (0.44) | KMT2AMEN1EGFRTP53 | |
| SCHEMBL21470297 | 0.78 | PTGER4 (0.49) | PTGER4KMT2AAGTR2AGTR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020107273-A1 | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | ASKAT INC. (JP) | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107273-A1 | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | PTGS1, PTGS2, OPRM1 | PTGER4 51/4885KMT2A 2917/4885MEN1 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.