Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6019118 | 0.99 | CYP2C19 (0.40) | CYP2C19LMNAHTTMAPTNPSR1 | |
| Ethylene Glycol SCHEMBL22654545 | 0.89 | CYP2C19 (0.45) | CYP2C19LMNAMAPTKDM4EKMT2A | |
| SCHEMBL1421114 | 0.89 | CYP2C19 (0.43) | CYP2C19LMNAMAPTKMT2AELANE | |
| SCHEMBL481232 | 0.89 | CYP2C19 (0.38) | CYP2C19LMNAHTTMAPTNPSR1 | |
| SCHEMBL3441077 | 0.88 | LMNA (0.43) | CYP2C19LMNAHTTMAPTNPSR1 | |
| SCHEMBL23855038 | 0.87 | LMNA (0.52) | CYP2C19LMNAHTTMAPTNPSR1 | |
| SCHEMBL8777327 | 0.87 | LMNA (0.52) | CYP2C19LMNAHTTMAPTNPSR1 | |
| Methacrylic Acid SCHEMBL7080056 | 0.87 | LMNA (0.49) | CYP2C19LMNAHTTMAPTNPSR1 | |
| SCHEMBL28300304 | 0.87 | LMNA (0.45) | LMNAHTTMAPTNPSR1KDM4E | |
| Acrylic Acid Ethyl Ester SCHEMBL11150751 | 0.87 | KDM4E (0.44) | CYP2C19LMNAKDM4EKMT2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148310-B2 | Multiple component coating composition utilizing dilution stable polyisocyanates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-12-12 | — | — | US | disclosed |
| WO-2005037936-A2 | MULTIPLE COMPONENT COATING COMPOSITION UTILIZING DILUTION STABLE POLYISOCYANATES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
| US-20050085614-A1 | Multiple component coating composition utilizing dilution stable polyisocyanates | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2005-04-21 | — | — | US | disclosed |